Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide, corresponding to residues in Human Glucose Transporter 8 (Uniprot: Q9NY64)
Applications
Application Notes
WB: 1/1000 - 1/5000;
Target
Alternative Names
SLC2A8; solute carrier family 2 (facilitated glucose transporter), member 8; solute carrier family 2 (facilitated glucose transporter) member 8; solute carrier family 2, facilitated glucose transporter member 8; GLUT8; GLUTX1; GLUT-8; glucose transporter
Product Background
Antigen Description
Glucose transporter 8 is an insulin-regulated facilitative glucose transporter. It binds cytochalasin B in a glucose-inhibitable manner. It appears to be a dual-specific sugar transporter as it can be inhibited by fructose. It is highly expressed in testis, where it is down-regulated by estrogen, but not in testicular carcinoma. Lower amounts are present in most other tissues.
Pathway
Facilitative Na+-independent glucose transporters, organism-specific biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds, organism-specific biosystem;
Citations
Publication ()
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COA
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