Anti-SLC2A6 monoclonal antibody (DCABH-640)

Mouse anti-Human SLC2A6 monoclonal antibody for WB, IHC-P, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
8F4
Species Reactivity
Human
Immunogen
Protein expressed in 293T cell transfected with Human Glucose Transporter GLUT6 expression vector.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500; IHC-P: 1/50; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SLC2A6; solute carrier family 2 (facilitated glucose transporter), member 6; solute carrier family 2, facilitated glucose transporter member 6; GLUT6; GLUT9; HSA011372
Entrez Gene ID
UniProt ID

Product Background


Gene summary
SLC2A6 (Solute Carrier Family 2 Member 6) is a Protein Coding gene. Diseases associated with SLC2A6 include hypouricemia, renal, 2 and testis seminoma. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and PAK Pathway. GO annotations related to this gene include transmembrane transporter activity and glucose transmembrane transporter activity. An important paralog of this gene is SLC2A8. Hexose transport into mammalian cells is catalyzed by a family of membrane proteins, including SLC2A6, that contain 12 transmembrane domains and a number of critical conserved residues.
Antigen Description
Facilitative glucose transporter; binds cytochalasin B with low affinity. Solute carrier family 2, facilitated glucose transporter member 6 is a protein that in humans is encoded by the SLC2A6 gene. 0The function about SLC2A6 antigen include glucose transmembrane transporter activity; substrate-specific transmembrane transporter activity.
Pathway
Facilitative Na+-independent glucose transporters, organism-specific biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds, organism-specific biosystem.

Citations


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References


Porpaczy, E; Bilban, M; et al. Gene expression signature of chronic lymphocytic leukaemia with Trisomy 12. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION 39:568-575(2009).
Rentoft, M; Coates, PJ; et al. Transcriptional Profiling of Formalin Fixed Paraffin Embedded Tissue: Pitfalls and Recommendations for Identifying Biologically Relevant Changes. PLOS ONE 7:-(2012).

Custom Antibody Labeling


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