Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
KLH conjugated synthetic peptide derived from human ENT2: 221-320/456
Applications
Application Notes
WB: 1:500-2000
IHC-P: 1:100-500
IHC-F: 1:100-500
IF: 1:100-500
General Notes
This product (Catalog No. DPABH-16153) is a rabbit-derived IgG polyclonal antibody raised against human SLC29A2, targeting the amino acid region 221–320 of the protein. This antibody exhibits cross-reactivity with SLC29A2 from mouse and rat. It has been affinity purified by Protein A. The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).
DPABH-16153 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500) applications.
DPABH-16153 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
DER12; Equilibrative NBMPR-insensitive nucleoside transporter; Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter; Equilibrative nucleoside transporter 2; HNP36; Hydrophobic nucleolar protein, 36 kDa; SLC29A2; solute carrier family 29 (nucleoside transporters), member 29; Solute carrier family 29 member 2; S29A2_HUMAN
Citations
Publication ()
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