SLC26A4 (NP_000432, 674 a.a. ~ 754 a.a) partial recombinant protein with GST tag. The sequence is RSLRVIVKEFQRIDVNVYFASLQDYVIEKLEQCGFFDDNIRKDTFFLTVHDAILYLQNQV KSQEGQGSILETITLIQDCKD
Conjugate
Unconjugated
Target
Alternative Names
SLC26A4; solute carrier family 26 (anion exchanger), member 4; EVA; PDS; DFNB4; TDH2B; pendrin; solute carrier family 26, member 4; sodium-independent chloride/iodide transporter;
Mutations in this gene are associated with Pendred syndrome, the most common form of syndromic deafness, an autosomal-recessive disease. It is highly homologous to the SLC26A3 gene; they have similar genomic structures and this gene is located 3 of the SLC26A3 gene. The encoded protein has homology to sulfate transporters.
Pathway
Multifunctional anion exchangers; Thyroid hormone synthesis; Transport of inorganic cations/anions and amino acids/oligopeptides;
Citations
Publication ()
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