SLC26A3 (NP_000102, 503 a.a. ~ 600 a.a) partial recombinant protein with GST tag. The sequence is TQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFFRRKLIDAVGF SPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDT
Conjugate
Unconjugated
Target
Alternative Names
SLC26A3; solute carrier family 26 (anion exchanger), member 3; CLD; DRA; chloride anion exchanger; down-regulated in adenoma protein; solute carrier family 26, member 3;
The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea.
Pathway
Mineral absorption; Multifunctional anion exchangers; Pancreatic secretion; Transmembrane transport of small molecules
Citations
Publication ()
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