General Notes
This product (Catalog No. DPABH-00652) is a rabbit-derived polyclonal antibody raised against human SLC25A22, targeting the amino acid region 128–188 of the protein. This antibody exhibits cross-reactivity with Human SLC25A22 from mouse, rat, and monkey. It has been affinity purified by Protein A. SLC25A22 encodes a mitochondrial glutamate/H+ symporter with highly expression in brain, especially in astrocytes, where it controls glutamate uptake. The mutations of SLC25A22 are associated with the early/infantile epileptic encephalopathies. It has been shown that SLC25A22 plays a key role in promoting proliferation and migration in cancer, such as human colorectal cancer (CRC) and Gallbladder cancer (GBC). And there is a result that the expression of SLC25A22 in GBC was significantly higher than that in adjacent tissues.
DPABH-00652 is suitable for use in Western blot (WB) (1:1,000–1:6,000), IHC (1:50–1:500), IF-P (1:50–1:500), IF/ICC (1:50–1:500) applications.
DPABH-00652 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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