General Notes
This product (Catalog No. DPABH-24119) is a rabbit-derived polyclonal antibody raised against human SLC24A3, targeting the amino acid region 361–450 of the protein. This antibody exhibits cross-reactivity with Human SLC24A3 from mouse and rat. It has been affinity purified by Protein A. SLC24A3, also known as NCKX3 (Na⁺/K⁺/Ca²⁺ exchanger 3), is a member of the solute carrier family 24 (SLC24), which comprises five K⁺-dependent Na⁺/Ca²⁺ exchangers (NCKX1-5). These transporters are critical for maintaining intracellular calcium homeostasis by coupling the extrusion of one Ca²⁺ ion and one K⁺ ion to the influx of four Na⁺ ions. SLC24A3 plays a key role in calcium signaling and homeostasis, influencing processes such as neurotransmission, smooth muscle contraction, and female reproductive physiology. Relatively high levels of SLC24A3 expression can be observed in heart tissue, consistent with the expression patterns reported in the literature. The observed molecular weight of SLC24A3 is 50-60 kDa, which is consistent with the literature description. (PMID: 21573014, PMID: 28588505).
DPABH-24119 is suitable for use in Western blot (WB) (1:500–1:2,000) application.
DPABH-24119 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.