Anti-SLC22A2 monoclonal antibody, clone FQS22359

Antibody Isotype

IgG

Clone

FQS22359

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human SLC22A2 aa 100-200. The exact sequence is proprietary.Database link: O15244

Conjugate

Application Notes

WB: 1/1000 - 1/5000; IHC-P: 1/100 - 1/250;

Alternative Names

SLC22A2; solute carrier family 22 (organic cation transporter), member 2; solute carrier family 22 member 2; OCT2; organic cation transporter 2; MGC32628;

Entrez Gene ID

UniProt ID

Antigen Description

SLC22A2 (solute carrier family 22 (organic cation transporter), member 2) is an organic cation transporter. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. SLC22A2 is found primarily in the kidney, where it may mediate the first step in cation reabsorption. It plays important roles in the renal tubular secretion of cationic drugs.

Pathway

Na+/Cl- dependent neurotransmitter transporters, organism-specific biosystem; Neuronal System, organism-specific biosystem; Neurotransmitter Clearance In The Synaptic Cleft, organism-specific biosystem; Neurotransmitter Release Cycle, organism-specific biosystem; Norepinephrine Neurotransmitter Release Cycle, organism-specific biosystem; Organic cation transport, organism-specific biosystem; Organic cation/anion/zwitterion transport, organism-specific biosystem;