Anti-SLC20A2 (aa 133-420) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant protein fragment, corresponding to an internal region within amino acids 133-420 of Human SLC20A2 (Uniprot ID Q08357)

Conjugate

Application Notes

WB: 1/500 - 1/3000.

Alternative Names

SLC20A2; solute carrier family 20 (phosphate transporter), member 2; GLVR2, MLVAR; sodium-dependent phosphate transporter 2; Glvr 2; PiT 2; gibbon ape leukemia virus receptor 2; murine leukemia virus, amphotropic, receptor for; PIT2; RAM1; GLVR2; IBGC3; M

Entrez Gene ID

UniProt ID

Antigen Description

Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Functions as a retroviral receptor and confers human cells susceptibility to infection to amphotropic murine leukemia virus (A-MuLV), 10A1 murine leukemia virus (10A1 MLV) and some feline leukemia virus subgroup B (FeLV-B) variants.

Pathway

SLC-mediated transmembrane transport; Sodium-coupled phosphate cotransporters; Transmembrane transport of small molecules; Transport of inorganic cations/anions and amino acids/oligopeptides;