Anti-SLC20A1 monoclonal antibody, clone FQS22538(3)

Antibody Isotype

IgG

Clone

FQS22538(3)

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human SLC20A1 aa 300-400 (Cysteine residue). The exact sequence is proprietary.Database link: Q8WUM9

Conjugate

Application Notes

ICC/IF: 1/50 - 1/100; IHC-P: 1/50 - 1/100; WB: 1/1000 - 1/5000; Flow Cyt: 1/10 - 1/100.

Alternative Names

SLC20A1; solute carrier family 20 (phosphate transporter), member 1; GLVR1; sodium-dependent phosphate transporter 1; gibbon ape leukemia virus receptor 1; Glvr 1; PiT 1; leukemia virus receptor 1 homolog; solute carrier family 20 member 1; PIT1; PiT-1; G

Entrez Gene ID

UniProt ID

Antigen Description

Sodium-phosphate symporter which plays a fundamental housekeeping role in phosphate transport, such as absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. May play a role in extracellular matrix and cartilage calcification as well as in vascular calcification. May function as a retroviral receptor as it confers human cells susceptibility to infection to Gibbon Ape Leukemia Virus (GaLV), Simian sarcoma-associated virus (SSAV) and Feline leukemia virus subgroup B (FeLV-B) as well as 10A1 murine leukemia virus (10A1 MLV).

Pathway

SLC-mediated transmembrane transport, organism-specific biosystem; Sodium-coupled phosphate cotransporters, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of inorganic cations/anions and amino acids/oligopeptides, organism-specific biosystem;