Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive)
Applications
Application Notes
WB: 1/10000 - 1/50000; IHC-P: 1/500 - 1/1000; ICC/IF: 1/100 - 1/250;
Target
Alternative Names
SLC1A1; solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1; excitatory amino acid transporter 3; EAAC1; EAAT3; excitatory amino acid carrier 1; solute carrier family 1 member 1; neuronal and epithelial
Product Background
Antigen Description
Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5.
Pathway
Glutamate Neurotransmitter Release Cycle, organism-specific biosystem; Glutamatergic synapse, organism-specific biosystem; Glutamatergic synapse, conserved biosystem; Neuronal System, organism-specific biosystem; Neurotransmitter Release Cycle, organism-specific biosystem; Protein digestion and absorption, organism-specific biosystem; Protein digestion and absorption, conserved biosystem.
Citations
Publication ()
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COA
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