Anti-SIX1 (full length) polyclonal antibody

Species Reactivity

Human

Immunogen

SIX1 (AAH08874, 1 a.a. ~ 284 a.a) full-length recombinant protein with GST tag. The sequence is MSMLPSFGFTQEQVACVCEVLQQGGNLERLGRFLWSLPACDHLHKNESVLKAKAVVAFHR GNFRELYKILESHQFSPHNHPKLQQLWLKAHYVEAEKLCGRPLGAVGKYRVRRKFPLPRT IWDGEETSYCFKEKSRGVLREWYAHNPYPSPREKRELAEATGLTTTQVSNWFKNRRQRDR AAEAKERENTENNNSSSNKQNQLSPLEGGKPLMSSSEEEFSPPQSPDQNSVLLLQGNMGH ARSSNYSLPGLTASQPSHGLQTHQHQLQDSLLGPLTSSLVDLGS

Conjugate

Alternative Names

SIX1; SIX homeobox 1; BOS3; TIP39; DFNA23; homeobox protein SIX1; sine oculis homeobox homolog 1;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a homeobox protein that is similar to the Drosophila sine oculis gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3).

Pathway

Transcriptional misregulation in cancer;