Specifications
Species Reactivity
Rabbit
Immunogen
Fusion protein, corresponding to amino acids 217-289 of Rabbit alpha Sarcoglycan
Applications
Application Notes
IHC-Fr: 1/100 - 1/200; WB: 1/250. Detects a band of approximately 50 kDa (predicted molecular weight: 43 kDa).
Target
Alternative Names
SGCA; sarcoglycan, alpha (dystrophin-associated glycoprotein); alpha-sarcoglycan; alpha-SG; 50 kDa dystrophin-associated glycoprotein; sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein); Asg; 50DAG; 59kDa; adhalin;
Product Background
Antigen Description
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Pathway
Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Hypertrophic cardiomyopathy (HCM), organism-specific biosystem; Hypertrophic cardiomyopathy (HCM), conserved biosystem; Viral myocarditis, organism-specific biosystem;
Citations
Publication ()
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COA
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