The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two pseudogenes, one on chromosome 15 and the other on chromosome 21, have been found for this gene.
Pathway
Cleavage of Growing Transcript in the Termination Region; Gene Expression; Herpes simplex infection; Processing of Capped Intron-Containing Pre-mRNA; RNA Polymerase II Transcription; Spliceosome; Transport of Mature Transcript to Cytoplasm; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3-end processing; mRNA Splicing; mRNA Splicing - Major Pathway;
Citations
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