Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) (C terminal)
Applications
Application Notes
WB: 1/1000 - 1/10000; Flow Cyt: 1/10 - 1/100.
Target
Alternative Names
SF3A3; splicing factor 3a, subunit 3, 60kDa; splicing factor 3a, subunit 3, 60kD; splicing factor 3A subunit 3; PRP9; PRPF9; SAP61; SF3a60; SAP 61; spliceosome associated protein 61; spliceosome-associated protein 61; pre-mRNA splicing factor SF3a (60kD);
Product Background
Antigen Description
SF3A3 is subunit 3 of the splicing factor SF3A. Splicing factor 3a is a heterotrimer consisting of subunits 1, 2 and 3, and is necessary for the conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. SF3A interacts with the pre-mRNA branch site early during spliceosome formation.
Pathway
Diurnally regulated genes with circadian orthologs, organism-specific biosystem; Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Spliceosome, organism-specific biosystem; Spliceosome, conserved biosystem; Spliceosome, U2-snRNP, organism-specific biosystem; mRNA Splicing, organism-specific biosystem;
Citations
Publication ()
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COA
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