Specifications
Immunogen
Recombinant full length protein of Human SerpinB6 produced in HEK293T cells (NP_004559).
Applications
Application Notes
WB: 1/500 - 1/2000; IHC-P: 1/150;
Target
Alternative Names
SERPINB6; serpin peptidase inhibitor, clade B (ovalbumin), member 6; deafness, autosomal recessive 91 , DFNB91, PI6, serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 6; serpin B6; CAP; cytoplasmic antiproteinase; PTI; PI-6; protease
Product Background
Antigen Description
May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.
Pathway
Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem;
Citations
Publication ()
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COA
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