Specifications
Immunogen
Recombinant fragment corresponding to Human Thyroxine Binding Globulin aa 168-302. Expressed in E. Coli.Sequence: AAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPS KTEDSSSFLIDKTTTVQVPMMHQMEQYYHLVDMELNCTVLQMDYSKNALA LFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGWVD Dat
Applications
Application Notes
WB: 1/500 - 1/2000;
Target
Alternative Names
SERPINA7; serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7; serine (or cysteine) proteinase inhibitor, clade A (alpha 1 antiproteinase, antitrypsin), member 7 , TBG; thyroxine-binding globulin; alpha 1 antiproteinase; an
Product Background
Antigen Description
The protein encoded by this gene is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. It is found in secretory vesicles of neurons and endocrine cells. This gene product is a precursor to three biologically active peptides; vasostatin, pancreastatin, and parastatin. These peptides act as autocrine or paracrine negative modulators of the neuroendocrine system. Other peptides, including chromostatin, beta-granin, WE-14 and GE-25, are also derived from the full-length protein. However, biological activities for these molecules have not been shown.
Citations
Publication ()
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COA
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