SEMA3B (NP_004627, 651 a.a. ~ 748 a.a) partial recombinant protein with GST tag. The sequence is FTQPLRRLSLHVLSATQAERLARAEEAAPAAPPGPKLWYRDFLQLVEPGGGGSANSLRMC RPQPALQSLPLESRRKGRNRRTHAPEPRAERGPRSATH
The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants.
Pathway
Axon guidance;
Citations
Publication ()
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