Anti-SELV polyclonal antibody (DPABH-08539)

Rabbit anti-Human SELV (aa 303-332) polyclonal antibody for WB, ICC/IF, FC, IHC-P Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic peptide within Human SELV aa 303-332 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: P59797
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/100 - 1/500. ICC/IF: 1/10 - 1/50. Flow Cyt: 1/10 - 1/50. IHC-P: 1/50 - 1/100.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Entrez Gene ID
UniProt ID

Product Background


Gene summary
SELV (Selenoprotein V) is a Protein Coding gene. Among its related pathways are Selenium Pathway and Selenium Metabolism and Selenoproteins. GO annotations related to this gene include selenium binding. An important paralog of this gene is SEPW1. This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.
Antigen Description
May be involved in a redox-related process.

Citations


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References


McCann, JC; Ames, BN; et al. Adaptive dysfunction of selenoproteins from the perspective of the triage theory: why modest selenium deficiency may increase risk of diseases of aging. FASEB JOURNAL 25:1793-1814(2011).
Lobanov, AV; Hatfield, DL; et al. Eukaryotic selenoproteins and selenoproteomes. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1790:1424-1428(2009).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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