This gene encodes a selenoprotein, which contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3 UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.
Pathway
Ether lipid metabolism; Glycerophospholipid biosynthesis; Glycerophospholipid metabolism; Metabolism; Metabolism of lipids and lipoproteins; Phosphatidylethanolamine (PE) biosynthesis, ethanolamine PE; Phosphatidylethanolamine (PE) biosynthesis, ethanolamine PE; Phospholipid metabolism; Selenium Metabolism and Selenoproteins; Selenium Pathway; Synthesis of PE;
Citations
Publication ()
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