Specifications
Immunogen
A synthetic peptide of human SEC31A is used for rabbit immunization.
Target
Alternative Names
SEC31A; SEC31 homolog A (S. cerevisiae); Sec31 homolog A (S. cerevisiae) , SEC31 like 1 (S. cerevisiae) , SEC31L1; protein transport protein Sec31A; ABP125; ABP130; KIAA0905; web1-like protein; SEC31-like protein 1; yeast Sec31p homolog; SEC31-related pro
Product Background
Antigen Description
The protein encoded by this gene is similar to yeast Sec31 protein. Yeast Sec31 protein is known to be a component of the COPII protein complex which is responsible for vesicle budding from endoplasmic reticulum (ER). This protein was found to colocalize with SEC13, one of the other components of COPII , in the subcellular structures corresponding to the vesicle transport function. An immunodepletion experiment confirmed that this protein is required for ER-Golgi transport. Alternative splicing results in multiple transcript variants encoding different isoforms.
Pathway
Activation of Chaperone Genes by XBP1(S), organism-specific biosystem; Activation of Chaperones by IRE1alpha, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; Antigen Presentation: Folding, assembly and peptide loading of class I MHC, organism-specific biosystem; Asparagine N-linked glycosylation, organism-specific biosystem; COPII (Coat Protein 2) Mediated Vesicle Transport, organism-specific biosystem; COPII complex, organism-specific biosystem.
Citations
Publication ()
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COA
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