Recombinant fragment, corresponding to a region within C terminal amino acids 788-1032 of Human SEC24D (UniProt O94855).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/500 - 1/3000.
Target
Alternative Names
SEC24D; SEC24 family, member D (S. cerevisiae); SEC24 (S. cerevisiae) related gene family, member D; protein transport protein Sec24D; KIAA0755; SEC24-related protein D; SEC24 related gene family, member D; FLJ43974;
Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex.
Pathway
Adaptive Immune System; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Asparagine N-linked glycosylation; COPII (Coat Protein 2) Mediated Vesicle Transport; COPII complex; Class I MHC mediated antigen processing & presentation
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Ohisa, S; Inohaya, K; et al. sec24d encoding a component of COPII is essential for vertebra formation, revealed by the analysis of the medaka mutant, vbi. DEVELOPMENTAL BIOLOGY 342:85-95(2010).
Adams, E; Baines, A; et al. The Role of Mammalian COPII Component SEC24D. MOLECULAR BIOLOGY OF THE CELL 22:-(2011).
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COA
Certificate of Analysis