General Notes
This product (Catalog No. DPABH-21806) is a rabbit-derived polyclonal antibody raised against human SEC14L2, targeting the amino acid region 1–403 of the protein. It has been affinity purified by Protein A. SEC14L2 is a protein-coding gene in humans located on chromosome 22q12.2 that encodes SEC14-like protein 2, a 403-amino acid cytosolic carrier protein belonging to the SEC14 family of lipid-binding proteins. This protein features a conserved CRAL_TRIO (cellular retinaldehyde-binding protein and three open reading frames) domain, which enables high-affinity binding to hydrophobic molecules such as alpha-tocopherol (vitamin E), phospholipids (including phosphatidylcholine, phosphatidylinositol, and phosphatidylglycerol), and squalene. Through these interactions, SEC14L2 facilitates the intracellular transport of lipids between membranes, potentially contributing to cholesterol metabolism by stimulating squalene monooxygenase activity.
DPABH-21806 is suitable for use in ELISA (1:4,000–1:8,000), IHC (1:50–1:100), Western blot (WB) (1:1,000–1:4,000) applications.
DPABH-21806 is supplied as a liquid formulation in 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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