Specifications
Immunogen
A synthetic peptide of human SEC11A is used for rabbit immunization.
Target
Alternative Names
SEC11A; SEC11 homolog A (S. cerevisiae); SPC18; SPCS4A; SEC11L1; sid2895; 1810012E07Rik; signal peptidase complex catalytic subunit SEC11A; endopeptidase SP18; SEC11-like protein 1; SPase 18 kDa subunit; signal peptidase complex (18kD); microsomal signal
Product Background
Antigen Description
This gene encodes a member of the peptidase S26B family. The encoded protein is an 18kDa subunit of the signal peptidase complex and has been linked to cell migration and invasion, gastric cancer and lymph node metastasis. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 8.
Pathway
Gene Expression; Incretin Synthesis, Secretion, and Inactivation; Metabolism of proteins; Peptide hormone metabolism; Protein export; SRP-dependent cotranslational protein targeting to membrane; Synthesis, Secretion, and Deacylation of Ghrelin; Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1); Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP); Translation.
Citations
Publication ()
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COA
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