RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting step that generates retinaldehyde from retinol (Matsuzaka et al., 2002 [PubMed 12372410]).
Pathway
Retinol metabolism, organism-specific biosystem; Retinol metabolism, conserved biosystem; retinoate biosynthesis I, conserved biosystem; retinoate biosynthesis I, organism-specific biosystem.
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