Specifications
Immunogen
Full length protein corresponding to Human SCNN1B aa 1-640.Sequence: MHVKKYLLKGLHRLQKGPGYTYKELLVWYCDNTNTHGPKRTICEGPKKKA MWFLLTLLFAALVCWQWGIFIRTYLSWEVSVSLSVGFKTMDFPAVTICNA SPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRNLNFSIWNHTPL VLIDERNPHHPMVLDLFGDNHNGLTSSSASEKI
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
SCNN1B; sodium channel, non-voltage-gated 1, beta subunit; sodium channel, non voltage gated 1, beta; sodium channel, nonvoltage gated 1, beta; amiloride-sensitive sodium channel subunit beta; ENaCbeta; Liddle syndrome; beta-ENaC; beta-NaCH; epithelial Na
Product Background
Antigen Description
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Pathway
Aldosterone-regulated sodium reabsorption; Taste transduction;
Citations
Publication ()
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COA
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