Synthesized peptide derived from internal of human SCN4A.
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:3000
General Notes
This product (Catalog No. DPABH-16987) is a rabbit-derived IgG polyclonal antibody raised against human SCN4A. It has been affinity purified by protein A. Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders. DPABH-16987 is suitable for use in Western blot (WB) (1:500–1:3,000) application. DPABH-16987 is supplied as a liquid formulation in PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
Sodium channel protein type 4 subunit alpha; Sodium channel protein type IV subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.4; Sodium channel protein skeletal muscle subunit alpha; SkM1
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