Anti-SCARA5 polyclonal antibody (DPABH-12400)

Rabbit Anti-Human SCARA5 (C-terminal) polyclonal antibody for ELISA, ICC, WB, IHC-P

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
17 amino acid synthetic peptide near the carboxy terminus of Human SCARA5.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1 - 2 μg/ml; IHC-P: 5 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SCARA5; scavenger receptor class A, member 5 (putative); scavenger receptor class A member 5; FLJ23907; MGC45780; NET33
Entrez Gene ID
UniProt ID

Product Background


Antigen Description
Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1). The function about SCARA5 antigen include ferritin receptor activity; receptor activity; scavenger receptor activity.

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