Anti-SAR1B monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human SAR1B is used for rabbit immunization.

Conjugate

Alternative Names

SAR1B; secretion associated, Ras related GTPase 1B; ANDD; CMRD; GTBPB; SARA2; GTP-binding protein SAR1b; 2310075M17Rik; SAR1 homolog B; SAR1a gene homolog 2; GTP-binding protein B; GTP-binding protein Sara;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.

Pathway

Adaptive Immune System; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Asparagine N-linked glycosylation; COPII (Coat Protein 2) Mediated Vesicle Transport; COPII complex;Chylomicron-mediated lipid transport; Class I MHC mediated antigen processing & presentation; ER to Golgi Transport; Immune System; Legionellosis;