This product (Catalog No. DPABH-22397) is a rabbit-derived polyclonal antibody raised against human SAR1A. This antibody exhibits cross-reactivity with Human SAR1A from mouse and rat. It has been affinity purified by Protein A. SAR1A, also named as SAR1, SARA and SARA1, belongs to the small GTPase superfamily and SAR1 family. It is involved in transport from the endoplasmic reticulum to the Golgi apparatus. SAR1A is required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES). DPABH-22397 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:50–1:500), IF/ICC (1:200–1:800) applications. DPABH-22397 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
SARA; SAR1; GTP binding protein SAR1a; EC:3.6.5.2; COPII-associated small GTPase
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