Anti-SAMHD1 monoclonal antibody (DCABH-1981) Knockout Validated

Mouse anti-Human SAMHD1 monoclonal antibody for WB, IHC-P, FC, ICC/IF

Specifications


Host Species
Mouse
Antibody Isotype
IgG2b
Clone
2B2
Species Reactivity
Mouse, Rat, Dog, Human, Monkey
Immunogen
Recombinant full length Human SAMHD1 produced in HEK293T cells (NP_056289).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/2000; IHC-P: 1/150; Flow Cyt: 1/100; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SAMHD1; SAM domain and HD domain 1; SAM domain and HD domain-containing protein 1; AGS5; Aicardi Goutieres syndrome 5; HD domain containing 1
Entrez Gene ID
UniProt ID

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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Mouse IgG2b Isotype Control DAGIC1236 FC EIA WB Mouse PDF Inquiry

References


Welbourn, S; Dutta, SM; et al. Restriction of Virus Infection but Not Catalytic dNTPase Activity Is Regulated by Phosphorylation of SAMHD1. JOURNAL OF VIROLOGY 87:11516-11524(2013).
Bloch, N; O'Brien, M; et al. HIV Type 1 Infection of Plasmacytoid and Myeloid Dendritic Cells Is Restricted by High Levels of SAMHD1 and Cannot be Counteracted by Vpx. AIDS RESEARCH AND HUMAN RETROVIRUSES 30:195-203(2014).

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