Anti-SAE1 polyclonal antibody (DPABH-22985)

Rabbit anti-Human SAE1 polyclonal antibody for WB, ELISA Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide corresponding to a region surrounding serine 185 of Human SAE1.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/3,000; ELISA:1/5000 - 1/25000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SAE1; SUMO1 activating enzyme subunit 1; AOS1; SUA1; UBLE1A; HSPC140
Entrez Gene ID
UniProt ID

Product Background


Pathway
Metabolism of proteins; Processing and activation of SUMO; SUMO is transferred from E1 to E2 (UBE2I, UBC9); Ubiquitin mediated proteolysis

Citations


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References


Tarricone, E; Ghirardello, A; et al. Anti-SAE antibodies in autoimmune myositis: Identification by unlabelled protein immunoprecipitation in an Italian patient cohort. JOURNAL OF IMMUNOLOGICAL METHODS 384:128-134(2012).
Tarricone, E; Ghirardello, A; et al. AUTOANTIBODY DETECTION IN SERUM OF PATIENTS WITH AUTOIMMUNE MYOSITIS: IDENTIFICATION OF ANTI-SAE1/SAE2 ANTIBODIES BY UNLABELLED PROTEIN IMMUNOPRECIPITATION. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 29:182-182(2011).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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