Anti-SAE1 polyclonal antibody (DPABH-22985)
Rabbit anti-Human SAE1 polyclonal antibody for WB, ELISA
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A synthetic peptide corresponding to a region surrounding serine 185 of Human SAE1.
WB: 1/500 - 1/3,000; ELISA:1/5000 - 1/25000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
SAE1; SUMO1 activating enzyme subunit 1; AOS1; SUA1; UBLE1A; HSPC140
Metabolism of proteins; Processing and activation of SUMO; SUMO is transferred from E1 to E2 (UBE2I, UBC9); Ubiquitin mediated proteolysis
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Tarricone, E; Ghirardello, A; et al. Anti-SAE antibodies in autoimmune myositis: Identification by unlabelled protein immunoprecipitation in an Italian patient cohort. JOURNAL OF IMMUNOLOGICAL METHODS 384:128-134(2012).
Tarricone, E; Ghirardello, A; et al. AUTOANTIBODY DETECTION IN SERUM OF PATIENTS WITH AUTOIMMUNE MYOSITIS: IDENTIFICATION OF ANTI-SAE1/SAE2 ANTIBODIES BY UNLABELLED PROTEIN IMMUNOPRECIPITATION. CLINICAL AND EXPERIMENTAL RHEUMATOLOGY 29:182-182(2011).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.