Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human CRALBP aa 1-100. The exact sequence is proprietary.Database link: P12271
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/1000 - 1/10000; IP: 1/40 - 1/60;
Target
Alternative Names
RLBP1; retinaldehyde binding protein 1; retinaldehyde-binding protein 1; CRALBP; cellular retinaldehyde-binding protein; cellular retinaldehyde-binding protein-1; MGC3663;
Soluble retinoid carrier essential the proper function of both rod and cone photoreceptors. Participates in the regeneration of active 11-cis-retinol and 11-cis-retinaldehyde, from the inactive 11-trans products of the rhodopsin photocycle and in the de novo synthesis of these retinoids from 11-trans metabolic precursors. The cycling of retinoids between photoreceptor and adjacent pigment epithelium cells is known as the visual cycle.
Pathway
Vitamin A and carotenoid metabolism, organism-specific biosystem; the visual cycle, conserved biosystem; the visual cycle, organism-specific biosystem.
Citations
Publication ()
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