Rabbit Anti-Human TRPV1 (internal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide corresponding to a region derived from internal residues of human transient receptor potential cation channel, subfamily V, member 1

Conjugate

Application Notes

IHC: 1:25-1:100

General Notes

This product (Catalog No. CPBT-49653RR) is a rabbit-derived polyclonal antibody raised against human TRPV1. It has been affinity purified by Protein A. Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.
CPBT-49653RR is suitable for use in IHC (1:25–1:100) application.
CPBT-49653RR is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

VR1

Entrez Gene ID

UniProt ID