Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human RRAD aa 50-150 (Cysteine residue). The exact sequence is proprietary.Database link: P55042
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/1000 - 1/5000; IP: 1/10 - 1/100;
Target
Alternative Names
RRAD; Ras-related associated with diabetes; GTP-binding protein RAD; RAD; REM3; ras associated with diabetes; RAS (RAD and GEM) like GTP binding 3; RAD1;
May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.
Pathway
Insulin Signaling, organism-specific biosystem.
Citations
Publication ()
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COA
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