Specifications
Immunogen
KLH conjugated synthetic peptide derived from human RPS4Y1: 121-220/263
Applications
Application Notes
IHC-P: 1:100-500
IHC-F: 1:100-500
IF: 1:100-500
General Notes
This product (Catalog No. DPABH-08949) is a rabbit-derived IgG polyclonal antibody raised against human RPS4Y1, targeting the amino acid region 121–220 of the protein. It has been affinity purified by Protein A. Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, X-linked (RPS4X). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
DPABH-08949 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500) applications.
DPABH-08949 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
40S ribosomal protein S4; 40S ribosomal protein S4, Y; 40S ribosomal protein S4, Y isoform 1; MGC119100; MGC5070; ribosomal protein S4, Y linked 1; ribosomal protein S4, Y linked; ribosomal protein S4, Y-linked 1; ribosomal protein S4Y; RPS4Y; RPS4Y1; RS4Y1_HUMAN; S4; Y isoform 1
Citations
Publication ()
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COA
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