Anti-RPLP2 polyclonal antibody (DPABH-04799)

Rabbit anti-Human RPLP2 (aa 1-99) polyclonal antibody for WB, IHC-P, ICC/IF Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Recombinant fragment, corresponding to a region within amino acids 1-99 of Human RPLP2 (P05387).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/500 - 1/3000; IHC-P: 1/100 - 1/1000; ICC/IF: 1/100 - 1/1000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
RPLP2; ribosomal protein, large, P2; D11S2243E; 60S acidic ribosomal protein P2; acidic ribosomal phosphoprotein P2; LP2
Entrez Gene ID
UniProt ID

Product Background


Gene summary
RPLP2 (Ribosomal Protein Lateral Stalk Subunit P2) is a Protein Coding gene. Diseases associated with RPLP2 include cysticercosis. Among its related pathways are Gene Expression and Metabolism. GO annotations related to this gene include RNA binding and structural constituent of ribosome. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Antigen Description
Plays an important role in the elongation step of protein synthesis. 60S acidic ribosomal protein P2 is a protein that in humans is encoded by the RPLP2 gene. 0The function about RPLP2 antigen include RNA binding; structural constituent of ribosome.
Pathway
Cap-dependent Translation Initiation; Cytoplasmic Ribosomal Proteins; Disease; Eukaryotic Translation Elongation; Eukaryotic Translation Initiation; Eukaryotic Translation Termination; Formation of a pool of free 4S subunits.

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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