Anti-RPL18A monoclonal antibody, clone 7H7H21

Antibody Isotype

IgG1

Clone

7H7H21

Species Reactivity

Mouse; Human

Immunogen

Purified recombinant fragment, corresponding to amino acids 50-176 of Human RPL18A, expressed in E. coli (UniProt: Q02543).

Conjugate

Application Notes

WB: 1/500 - 1/2000; ELISA: 1/10000; IHC-P: 1/200 - 1/1000; Flow Cyt: 1/200 - 1/400; ICC/IF: 1/200 - 1/1000;

Alternative Names

RPL18A; ribosomal protein L18a; 60S ribosomal protein L18a; L18A; ribosomal protein L18a like protein; ribosomal protein L18a-like protein;

Entrez Gene ID

UniProt ID

Antigen Description

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. RPL18A belongs to the L18AE family of ribosomal proteins. It is located in the cytoplasm. This gene is co-transcribed with the U68 snoRNA, which is located in its third intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Pathway

Cap-dependent Translation Initiation, organism-specific biosystem; Cytoplasmic Ribosomal Proteins, organism-specific biosystem; Disease, organism-specific biosystem; Eukaryotic Translation Elongation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Eukaryotic Translation Termination, organism-specific biosystem; Formation of a pool of free 40S subunits, organism-specific biosystem;