Synthetic peptide designed within residues: DFDPLVYCSP KGDPQRVDMQ PSVTSRPRSL DSVVPTGETQ VSSHVHYHRH, corresponding to internal sequence amino acids 504 - 553 of Human RNF43 (NP_060233)
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml; ICC/IF: 5 μg/ml;
Target
Alternative Names
RNF43; ring finger protein 43; URCC; RNF124; E3 ubiquitin-protein ligase RNF43;
RNF43 is a probable E3 ubiquitin-protein ligase that promotes cell growth and is upregulated in colon cancer. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Pathway
Signal Transduction; TCF dependent signaling in response to WNT;
Citations
Publication ()
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COA
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