RNF4 (NP_002929, 107 a.a. ~ 190 a.a) partial recombinant protein with GST tag. The sequence is YVTTHTPRNARDEGATGLRPSGTVSCPICMDGYSEIVQNGRLIVSTECGHVFCSQCLRDS LKNANTCPTCRKKINHKRYHPIYI
Conjugate
Unconjugated
Target
Alternative Names
RNF4; ring finger protein 4; SLX5; SNURF; RES4-26; E3 ubiquitin-protein ligase RNF4; E3 ubiquitin ligase RNF4; small nuclear RING finger protein;
The protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with, and inhibit the activity of, TRPS1, a transcription suppressor of GATA-mediated transcription. Transcription repressor ZNF278/PATZ is found to interact with this protein, and thus reduce the enhancement of androgen receptor-dependent transcription mediated by this protein. Studies of the mouse and rat counterparts suggested a role of this protein in spermatogenesis. A pseudogene of this gene is found on chromosome 1.[provided by RefSeq, Jul 2010]
Pathway
Adaptive Immune System; Antigen processing: Ubiquitination & Class I MHC mediated antigen processing & Immune System.
Citations
Publication ()
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