Full length protein corresponding to Human RNF138 aa 1-245. (NP_057355.2).Sequence: MAEDLSAATSYTEDDFYCPVCQEVLKTPVRTTACQHVFCRKCFLTAMRES GAHCPLCRGNVTRRERACPERALDLENIMRKFSGSCRCCAKQIKFYRMRH HYKSCKKYQDEYGVSSIIPNFQISQDSVGNSNRSETSTSDNTETYQENTS SSGHPTFKCPLCQESNFT
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
RNF138; ring finger protein 138, E3 ubiquitin protein ligase; ring finger protein 138; E3 ubiquitin-protein ligase RNF138; STRIN; NLK-associated RING finger protein; Nemo-like kinase-associated RING finger protein; NARF; HSD-4; hNARF; MGC8758;
E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway.
Pathway
Adaptive Immune System; Antigen processing: Ubiquitination & Proteasome degradation; Class I MHC mediated antigen processing & presentation; Immune System.
Citations
Publication ()
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