Synthetic peptide within Human RITA aa 43-72 (N terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: Q96K30
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/100 - 1/500;
Target
Alternative Names
RITA1; RBPJ interacting and tubulin associated 1; RITA; C12orf52; RBPJ-interacting and tubulin-associated protein 1;
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
Citations
Publication ()
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