General Notes
This product (Catalog No. DPABH-11823) is a rabbit-derived polyclonal antibody raised against human RIOK1, targeting the amino acid region 219–568 of the protein. This antibody exhibits cross-reactivity with Human RIOK1 from mouse and rat. It has been affinity purified by Protein A. RIOK1 (RIO Kinase 1) is a protein-coding gene located on chromosome 6 in humans. It encodes a serine/threonine-protein kinase that belongs to the RIO family of atypical protein kinases/ATPases. This family also includes RIOK2, RIOK3, and RIOB, which have evolved from Archaea to humans. RIOK1 is best known for its role in ribosome biogenesis and its involvement in various cellular processes, including translation regulation and cell-cycle progression. (PMID: 37301535, PMID: 37935656).
DPABH-11823 is suitable for use in Western blot (WB) (1:500–1:1,000), IP (0.5-4.0 μg for 1.0-3.0 mg of total protein lysate), IHC (1:500–1:2,000), IF/ICC (1:200–1:800) applications.
DPABH-11823 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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