Anti-RHOH (full length) polyclonal antibody

Species Reactivity

Human

Immunogen

RHOH (AAH14261.1, 1 a.a. ~ 191 a.a) full-length recombinant protein with GST tag. The sequence is MLSSIKCVLVGDSAVGKTSLLVRFTSETFPEAYKPTVYENTGVDVFMDGIQISLGLWDTA GNDAFRSIRPLSYQQADVVLMCYSVANHNSFLNLKNKWIGEIRSNLPCTPVLVVVTQTDQ REMGPHRASCVNAMEGKKLAQDVRAKGYLECSALSNRGVQQVFECAVRTAVNQARRRNRR RLFSINECKIF

Conjugate

Alternative Names

RHOH; ras homolog family member H; TTF; ARHH; rho-related GTP-binding protein RhoH; GTP-binding protein TTF; TTF, translocation three four; ras homolog gene family, member H;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkins lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5 untranslated region results in multiple transcript variants that encode the same protein.

Pathway

Leukocyte transendothelial migration; Signal Transduction;