Anti-RGS7BP (aa 86-178) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Recombinant fragment, corresponding to amino acids 86-178 of Human RGS7BP (Q6MZT1).

Conjugate

Application Notes

WB: 1/100 - 1/250; IHC-P: 1/50 - 1/200;

Alternative Names

RGS7BP; regulator of G-protein signaling 7 binding protein; R7BP; regulator of G-protein signaling 7-binding protein; R7 family-binding protein;

Entrez Gene ID

UniProt ID

Antigen Description

Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cypolasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation