Anti-RFX4 polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide (Human)

Conjugate

Application Notes

Peptide ELISA: 1/62500; WB: 0.25 μg/ml;

Alternative Names

RFX4; regulatory factor X, 4 (influences HLA class II expression); NYD-SP10; transcription factor RFX4; testis development protein NYD-SP10; winged-helix transcription factor RFX4;

Entrez Gene ID

UniProt ID

Antigen Description

RFX4 is a transcription factors that contain a highly-conserved winged helix DNA binding domain. RFX4 is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. RFX4 may be a transcriptional repressor rather than a transcriptional activator.This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X3, and X5. It has been shown to interact with itself as well as with regulatory factors X2 and X3, but it does not interact with regulatory factor X1. This protein may be a transcriptional repressor rather than a transcriptional activator. Three transcript variants encoding different isoforms have been described for this gene.