Anti-RFX1 (aa 502-600) polyclonal antibody

Species Reactivity

Human

Immunogen

RFX1 (NP_002909, 502 a.a. ~ 600 a.a) partial recombinant protein with GST tag. The sequence is SKYHYYGLRIKASSPLLRLMEDQQHMAMRGQPFSQKQRLKPIQKMEGMTNGVAVGQQPST GLSDISAQVQQYQQFLDASRSLPDFTELDLQGKVLPEGV

Conjugate

Alternative Names

RFX1; regulatory factor X, 1 (influences HLA class II expression); EFC; RFX; MHC class II regulatory factor RFX1; enhancer factor C; regulatory factor X 1; transcription factor RFX1; trans-acting regulatory factor 1; MHC class II regulatory factor RFX;

Entrez Gene ID

UniProt ID

Antigen Description

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X2, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with RFX family members X2, X3, and X5, but not with X4. This protein binds to the X-boxes of MHC class II genes and is essential for their expression. Also, it can bind to an inverted repeat that is required for expression of hepatitis B virus genes.