REXO2 (NP_056338, 101 a.a. ~ 210 a.a) partial recombinant protein with GST tag. The sequence is HGRSGLTKAVKESTITLQQAEYEFLSFVRQQTPPGLCPLAGNSVHEDKKFLDKYMPQFMK HLHYRIIDVSTVKELCRRWYPEEYEFAPKKAASHRALDDISESIKELQFY
This gene encodes a 3-to-5 exonuclease specific for small (primarily 5 nucleotides or less in length) single-stranded RNA and DNA oligomers. This protein may have a role in DNA repair, replication, and recombination, and in RNA processing and degradation. It may also be involved in resistance of human cells to UV-C-induced cell death through its role in the DNA repair process.
Pathway
Ribosome biogenesis in eukaryotes;
Citations
Publication ()
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