Rabbit Anti-Human RCL1 (C-terminal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human RCL1.

Conjugate

Application Notes

WB: 1:500-1:1000

General Notes

This product (Catalog No. DPABH-22560) is a rabbit-derived polyclonal antibody raised against human RCL1. This antibody exhibits cross-reactivity with RCL1 from mouse. It has been affinity purified by Protein A. RCL1 (RNA terminal phosphate cyclase-like 1) is a protein-coding gene in humans that encodes a nucleolar protein involved in the early stages of ribosomal small subunit biogenesis, particularly through its role in processing pre-ribosomal RNA to produce mature 18S rRNA. The gene is located on the short arm of chromosome 9 at position 9p24.1 and consists of 10 exons, producing multiple transcript isoforms, with the canonical isoform encoding a 371-amino-acid protein containing an RTC domain characteristic of RNA 3'-terminal phosphate cyclases. Although named for its similarity to RNA terminal phosphate cyclases, RCL1 functions primarily as an endonuclease rather than a cyclase, lacking key catalytic residues for the latter activity.[.
DPABH-22560 is suitable for use in Western blot (WB) (1:500–1:1,000) application.
DPABH-22560 is supplied as a liquid formulation in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

RNAC; RPC2; RPCL1; RTC2; RNA 3'-terminal phosphate cyclase-like protein; RCL1; RNA terminal phosphate cyclase-like 1

Entrez Gene ID

UniProt ID