RBAK (NP_066986, 51 a.a. ~ 150 a.a) partial recombinant protein with GST tag. The sequence is TTKPNVIIKLEQGEEPWIMGGEFPCQHSPEAWRVDDLIERIQENEDKHSRQAACINSKTL TEEKENTFSQIYMETSLVPSSIIAHNCVSCGKNLESISQL
This gene encodes a nuclear protein which interacts with the tumor suppressor retinoblastoma 1. The two interacting proteins are thought to act as a transcriptional repressor for promoters which are activated by the E2F1 transcription factor. This protein contains a Kruppel-associated box (KRAB), which is a transcriptional repressor motif. Read-through transcripts that include exons from the downstream gene LOC389458 are expressed from this locus.
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